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| 王克坚 博士
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Dr. Wang Kejian
Minjiang Chair Professor |
Tel: 0592-2184658
Email: wkjian@xmu.edu.cn
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个人简介 |
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个人履历
Brief CV |
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中国人民解放军军需大学博士（1999）
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澳大利亚悉尼大学动物健康系访问学者（1993-1994）
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中国农业科学院特产研究所研究员（2000-2001）
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厦门大学教授（2001-）
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美国佛罗里达大学生理学与功能基因系高级访问学者 (2005-2006)
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"闽江学者"特聘教授 (2009-)
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PhD, Quartermaster University of PLA (1999)
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Visiting Scholar, Department of Animal Health, University of Sydney, Australia (1993-1994)
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Senior Principal Research Fellow, Chinese Academy of Agricultural Sciences (2000-2001)
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Professor, Xiamen University (2001-)
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Senior Visiting Scholar, Department of Physiology and Functional Genomics, University of Florida, USA (2005-2006)
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Mingjiang chair professor, Xiamen University (2009-).
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研究方向
Research Interests |
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海洋生物分子生物学与基因组学 (Marine Molecular Biology and Genomics )；海洋环境污染物的分子与免疫毒理学 (Molecular and Immunological Ecotoxicology Studies for the Marine Environmental Pollutants ); 转基因与基因工程（Transgenic and Genetic Engineering Studies）
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代表性论文
Selected Publications |
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Zhou, Y., Meng, X.Y., Chen, F.Y., Xiong, M., Zhang, W.B., Ke-Jian Wang* , Newly discovered antimicrobial peptide Scyampcin44-63 from Scylla paramamosain exhibits a multitargeted candidacidal mechanism in vitro and is effective in a murine model of vaginal candidiasis, Antimicrobial Agents and Chemotherapy, 2023, aac.00022-23.
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Zhang, W.B., An, Z., Bai, Y.Q., Zhou, Y., Chen, F.Y. *, Wang, K.J.* , A novel antimicrobial peptide Scyreptin1-30 from Scylla paramamosain exhibiting potential therapy of Pseudomonas aeruginosa early infection in a mouse burn wound model, Biochemical Pharmacology, 218 (2023) 115917.
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Zhu X., Chen F., Li S., Peng H., Wang, K.J.*, A Novel Antimicrobial Peptide Sparanegtin Identified in Scylla paramamosain Showing Antimicrobial Activity and Immunoprotective Role In Vitro and Vivo, International Journal of Molecular Science, 2022, 23, 15.
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Yang Y., Chen H.Y., Hao H., Wang K.J.*, The Anticancer Activity Conferred by the Mud Crab Antimicrobial Peptide Scyreprocin through Apoptosis and Membrane Disruption, International Journal of Molecular Science , 2022, 23, 5500.
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Yang, Y., Chen, F.Y., Qiao, K., Zhang, H., Chen, H.Y., Wang, K.J.* , Two Male-Specific Antimicrobial Peptides SCY2 and Scyreprocin as Crucial Molecules Participated in the Sperm Acrosome Reaction of Mud Crab Scylla paramamosain, International Journal of Molecular Sciences, 2022, 23, 3373.
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Zhu,D., Chen, F.Y., Chen, Y.C., Peng, H. and Wang, K.J.* , The Long-Term Effect of a Nine Amino-Acid Antimicrobial Peptide AS-hepc3(48-56) Against Pseudomonas aeruginosa With No Detectable Resistance, Frontiers in Cellular and Infection Microbiology ,2021.752637.
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Chen, Y.C., Yang, Y., Zhang, C., Chen, H.Y., Chen, F. Y.* and Wang, K.J.* , A Novel Antimicrobial Peptide Sparamosin26–54 From the Mud Crab Scylla paramamosain Showing Potent Antifungal Activity Against Cryptococcus neoformans, Frontiers in Microbiology , 2021.746006.
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Zhang, H., Yang, Y., Zhu, X.W., Liu, Y.Z., Chen, F.Y.*, Wang, K.J.* , A truncated peptide Sp-NPFin from the neuropeptide FII SpNPFII of Scylla paramamosain exhibiting potent antimicrobial activity, Aquaculture, 533 (2021) 736145.
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Yin, X.H., Liu, Y., Zeb, R., Chen, F.Y., Chen, H.Y., Wang, K.J.* , The intergenerational toxic effects on offspring of medaka fish Oryzias melastigma from parental benzo[a]pyrene exposure via interference of the circadian rhythm, Environmental Pollution, 267 (2020) 115437.
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Cui, Q, Chen, F.Y., Zhang, M., Peng, H., Wang, K.J.*.Transcriptomic analysis revealing hepcidin expression in Oryzias melastigma regulated through the JAK-STAT signaling pathway upon exposure to BaP, Aquatic Toxicology, 2019, 206, 134-141.
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Qiu, W.H.﹡, Fang, M., Liu, J., Fu, C., Zheng, C., Chen, B., Wang, K.J.*, In vivo actions of Bisphenol F on the reproductive neuroendocrine system after long-term exposure in zebrafish, Science of the Total Environment, 2019, 665: 995-1002
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