Honors Awards
Research Group
  欢迎光临 王克坚 博士的个人主页  

王克坚  博士

Dr. Wang Kejian
Minjiang Chair Professor
Tel: 0592-2184658
Email: wkjian@xmu.edu.cn
个人履历 Brief CV




  美国佛罗里达大学生理学与功能基因系高级访问学者 (2005-2006)

  "闽江学者"特聘教授 (2009-)

  PhD, Quartermaster University of PLA (1999)

  Visiting Scholar, Department of Animal Health, University of Sydney, Australia (1993-1994)

  Senior Principal Research Fellow, Chinese Academy of Agricultural Sciences (2000-2001)

  Professor, Xiamen University (2001-)

  Senior Visiting Scholar, Department of Physiology and Functional Genomics, University of Florida, USA (2005-2006)

  Mingjiang chair professor, Xiamen University (2009-).


研究方向 Research Interests
  海洋生物分子生物学与基因组学 (Marine Molecular Biology and Genomics );海洋环境污染物的分子与免疫毒理学 (Molecular and Immunological Ecotoxicology Studies for the Marine Environmental Pollutants ); 转基因与基因工程(Transgenic and Genetic Engineering Studies)

代表性论文 Selected Publications
  Zhou, Y., Meng, X.Y., Chen, F.Y., Xiong, M., Zhang, W.B., Ke-Jian Wang* , Newly discovered antimicrobial peptide Scyampcin44-63 from Scylla paramamosain exhibits a multitargeted candidacidal mechanism in vitro and is effective in a murine model of vaginal candidiasis, Antimicrobial Agents and Chemotherapy, 2023, aac.00022-23.

  Zhang, W.B., An, Z., Bai, Y.Q., Zhou, Y., Chen, F.Y. *, Wang, K.J.* , A novel antimicrobial peptide Scyreptin1-30 from Scylla paramamosain exhibiting potential therapy of Pseudomonas aeruginosa early infection in a mouse burn wound model, Biochemical Pharmacology, 218 (2023) 115917.

  Zhu X., Chen F., Li S., Peng H., Wang, K.J.*, A Novel Antimicrobial Peptide Sparanegtin Identified in Scylla paramamosain Showing Antimicrobial Activity and Immunoprotective Role In Vitro and Vivo, International Journal of Molecular Science, 2022, 23, 15.

  Yang Y., Chen H.Y., Hao H., Wang K.J.*, The Anticancer Activity Conferred by the Mud Crab Antimicrobial Peptide Scyreprocin through Apoptosis and Membrane Disruption, International Journal of Molecular Science , 2022, 23, 5500.

  Yang, Y., Chen, F.Y., Qiao, K., Zhang, H., Chen, H.Y., Wang, K.J.* , Two Male-Specific Antimicrobial Peptides SCY2 and Scyreprocin as Crucial Molecules Participated in the Sperm Acrosome Reaction of Mud Crab Scylla paramamosain, International Journal of Molecular Sciences, 2022, 23, 3373.

  Zhu,D., Chen, F.Y., Chen, Y.C., Peng, H. and Wang, K.J.* , The Long-Term Effect of a Nine Amino-Acid Antimicrobial Peptide AS-hepc3(48-56) Against Pseudomonas aeruginosa With No Detectable Resistance, Frontiers in Cellular and Infection Microbiology ,2021.752637.

  Chen, Y.C., Yang, Y., Zhang, C., Chen, H.Y., Chen, F. Y.* and Wang, K.J.* , A Novel Antimicrobial Peptide Sparamosin26–54 From the Mud Crab Scylla paramamosain Showing Potent Antifungal Activity Against Cryptococcus neoformans, Frontiers in Microbiology , 2021.746006.

  Zhang, H., Yang, Y., Zhu, X.W., Liu, Y.Z., Chen, F.Y.*, Wang, K.J.* , A truncated peptide Sp-NPFin from the neuropeptide FII SpNPFII of Scylla paramamosain exhibiting potent antimicrobial activity, Aquaculture, 533 (2021) 736145.

  Yin, X.H., Liu, Y., Zeb, R., Chen, F.Y., Chen, H.Y., Wang, K.J.* , The intergenerational toxic effects on offspring of medaka fish Oryzias melastigma from parental benzo[a]pyrene exposure via interference of the circadian rhythm, Environmental Pollution, 267 (2020) 115437.

  Cui, Q, Chen, F.Y., Zhang, M., Peng, H., Wang, K.J.*.Transcriptomic analysis revealing hepcidin expression in Oryzias melastigma regulated through the JAK-STAT signaling pathway upon exposure to BaP, Aquatic Toxicology, 2019, 206, 134-141.