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Marine pollution, ecotoxicology and sustainability
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Antibiotics in the Coastal Environment of the East China Sea: Levels, Distribution and Impact Factors
Monday 7th @ 1410-1430, Conference Room 7
Feifei Li* , 1 School of Water Resources and Environment, China University of Geosciences, Beijing 100083 China;
2 School of Environment, TsingHua University, Beijing 100084, China;
Donghui Wen, College of Environmental Sciences and Engineering, Peking University, Beijing 100871, China;
Chuanping Feng, School of Water Resources and Environment, China University of Geosciences, Beijing 100083 China;
Lujun Chen, 1.School of Environment, TsingHua University, Beijing 100084, China;
2.Zhejiang Provincial Key Laboratory of Water Science and Technology, Zhejiang 314006, China;
Bei Huang, Zhejiang Provincial Zhoushan Marine Ecological Environmental Monitoring Station, Zhoushan 316021, China
Qinglin Mu, Zhejiang Provincial Zhoushan Marine Ecological Environmental Monitoring Station, Zhoushan 316021, China
Presenter Email: feifeili0901@163.com |
The levels and distribution of 28 antibiotics from 3 categories in the coastal area of the East China Sea were investigated using solid-phase extraction coupled with ultra-performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS). The seawater and surface sediment samples were collected from 20 sites, covering the Hangzhou Bay (HZB), Xiangshan Bay (XSB) and Taizhou Bay (TZB). The results showed that 17 antibiotics, including 10 sulfonamides (SAs), 5 macrolides (MLs), and 2 Lincomycins (LMs), were frequently detected in both seawater and sediment samples. The total concentration of these 17 widely presented antibiotics in the coastal areas ranged in 5.17 – 2173.04 ng/L in the seawater, and specifically the concentrations of SAs, MLs, and LMs ranged in 3.76 - 607.72 ng/L, 0.19 - 4.97 ng/L and 1.76 - 1563.13 ng/L, contributing 32.31%, 0.50%, and 67.19% to the total antibiotics burden, respectively. Sulfamonomethoxine, sulfaquinoxaline, clindamycin hydrochloride and lincomycin hydrochloride were the main antibiotic species in the seawater, which contributed 12.79%, 9.14%, 58.90% and 8.30% to the total antibiotic burden, respectively. The total concentrations of the presented antibiotics ranged in 11.42 - 108.78 ng/L, 5.71 - 32.59 ng/L, and 36.98 - 2173.04 ng/L in HZB, XSB and TZB, respectively. In addition, the main antibiotic category was SAs contributing 89.30% and 62.04% to the total antibiotic burden in HZB and XSB, respectively. However, LMs was the main antibiotic category contributing 74.52% to the total antibiotic burden in TZB. In sediment samples, the concentrations of MLs and LMs ranged in 0.08 - 1.32 ng/g and ND - 2.93 ng/g. Moreover, the relevance relationship between antibiotics and water quality and sediment properties was explored. The results showed that antibiotic concentration in seawater was significantly negatively correlated (p<0.05) with salinity, DO and pH, but positively correlated (p<0.05) with SS, PO43+, COD, NO3-, petroleum and As, and has no correlation with NO2-, Hg, Cu, Pb and Cd. Meanwhile, antibiotic concentration in sediments had the same relevance relationship with sediment properties as them in the seawater. |
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