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| 王克坚 博士
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Dr. Wang Kejian
Minjiang Chair Professor |
Tel: 0592-2184658
Email: wkjian@xmu.edu.cn
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个人简介 |
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个人履历
Brief CV |
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中国人民解放军军需大学博士（1999）
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澳大利亚悉尼大学动物健康系访问学者（1993-1994）
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中国农业科学院特产研究所研究员（2000-2001）
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厦门大学教授（2001-）
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美国佛罗里达大学生理学与功能基因系高级访问学者 (2005-2006)
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"闽江学者"特聘教授 (2009-)
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PhD, Quartermaster University of PLA (1999)
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Visiting Scholar, Department of Animal Health, University of Sydney, Australia (1993-1994)
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Senior Principal Research Fellow, Chinese Academy of Agricultural Sciences (2000-2001)
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Professor, Xiamen University (2001-)
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Senior Visiting Scholar, Department of Physiology and Functional Genomics, University of Florida, USA (2005-2006)
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Mingjiang chair professor, Xiamen University (2009-).
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研究方向
Research Interests |
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海洋生物分子生物学与基因组学 (Marine Molecular Biology and Genomics )；海洋环境污染物的分子与免疫毒理学 (Molecular and Immunological Ecotoxicology Studies for the Marine Environmental Pollutants ); 转基因与基因工程（Transgenic and Genetic Engineering Studies）
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代表性论文
Selected Publications |
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Zhou, Z.Z., Chen, F.Y.*, Hao, H.,Ke-Jian Wang* , A novel antimicrobial peptide Larimicin78-102 from large yellow croaker (Larimichthys crocea) shows potent antibacterial activity in vitro and enhances resistance to vibrio fluvialis infection in vivo, Fish and Shellfish Immunology 161 (2025) 110279.
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Meng, X.Z., Duan, Y.Y., Bai, Y.Q., Zhang, W.B., Zhang, C., Chen, F.Y.*, Ke-Jian Wang* , The antimicrobial peptide Sparamosin26–54 exhibits antiviral activity against three aquatic enveloped viruses through lipid-binding-mediated virus lysis, Aquaculture, 592(2024)741160.
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Bai, Y.Q., Zhang, W.B., Zheng, W.B., Meng, X.Z., Duan, Y.Y., Zhang, C., Chen, F.Y.*， Ke-Jian Wang* , A 14-amino acid cationic peptide Bolespleenin334-347 from the marine fish mudskipper Boleophthalmus pectinirostris exhibiting potent antimicrobial activity and therapeutic potential , Biochemical Pharmacology, 226(2024)116344.
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Sun, H., Chen, F.Y., H., Hao, Xiong, M., Peng, H.,An, Z., Ke-Jian Wang*, Benefcial efects of AMP Scy-hepc on the gut microbiota contribute to the potential growth of Larimichthys crocea, Blue Biotechnology, (2024) 1:11
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Zhang, C., Chen, F.Y.*, Bai, Y.Q., Dong, X.X., Meng, X.Z., Ke-Jian Wang* , A novel antimicrobial peptide Spasin141-165 identified from Scylla paramamosain exhibiting protection against Aeromonas hydrophila infection, Aquaculture, 591(2024)741137.
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Zhou, Y., Meng, X.Y., Chen, F.Y., Xiong, M., Zhang, W.B., Ke-Jian Wang* , Newly discovered antimicrobial peptide Scyampcin44-63 from Scylla paramamosain exhibits a multitargeted candidacidal mechanism in vitro and is effective in a murine model of vaginal candidiasis, Antimicrobial Agents and Chemotherapy, 2023, aac.00022-23.
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An, Z., Chen, F.Y., Hao, H., Xiong, M., Peng, H., Sun, H., Ke-Jian Wang* ,Growth- promoting effect of antimicrobial peptide Scy-hepc on mariculture large yellow croaker Larimichthys crocea and the underlying mechanism, Fish and Shellfish Immunology , 2023,108649.
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Zhang, W.B., An, Z., Bai, Y.Q., Zhou, Y., Chen, F.Y. *, Ke-Jian Wang* , A novel antimicrobial peptide Scyreptin1-30 from Scylla paramamosain exhibiting potential therapy of Pseudomonas aeruginosa early infection in a mouse burn wound model, Biochemical Pharmacology, 218 (2023) 115917.
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Yang Y., Chen H.Y., Hao H., Ke-Jian Wang*, The Anticancer Activity Conferred by the Mud Crab Antimicrobial Peptide Scyreprocin through Apoptosis and Membrane Disruption, International Journal of Molecular Science , 2022, 23, 5500.
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Yang, Y., Chen, F.Y., Qiao, K., Zhang, H., Chen, H.Y., Ke-Jian Wang* , Two Male-Specific Antimicrobial Peptides SCY2 and Scyreprocin as Crucial Molecules Participated in the Sperm Acrosome Reaction of Mud Crab Scylla paramamosain, International Journal of Molecular Sciences, 2022, 23, 3373.
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